… perform a comprehensive solid forms screen and a full evaluation and comparison with the
relevant patent literature in order to assemble all the pieces of the solid forms puzzle of APX. …

… apixaban solubility and thermodynamic features of apixaban … of equilibrated solids, signifying
that apixaban presents in … the drug apixaban used in this contribution belongs to form I. …

… Physical properties of crystalline form depend on the … to form salts. Thus, this method is not
limited to only ionizable APIs. Overall, cocrystallization process leads to the self-assembly of …

… The solubility profile of apixaban in pure and mixed solvents within the temperature range
from (… The solid state of apixaban in equilibrated form was characterized using powder X-ray …

… At first, Zn 4 O(Ac) 6 tetrahedrons form, which then aggregate through a series of magic
clusters. For the time, a quantitative model for this detailed growth chemistry does not exist. …

… Lately, however, two important pieces of the puzzle emerge, … aspirin to prevent several
cancer types. The ukCAP trial suggest … in fact, solid cancer rates after apixaban were more than …

… behavior reminiscent of a sliding puzzle, where their mobility … their pure solid forms, but lower
than that of their liquid forms. … It also balances fitting data without overfitting by building the …

… for NC solids. This suggests that treating NC surfaces with EDLs can form an effective … of κ
D = 1.22 ns –1 , which is obtained by fitting the TA spectra of colloidal PDTC-exchanged NCs (…

… The characteristics of the three types of chromatographic peaks and their first and … fitting.
The part 4 from the right is taken as an example to demonstrate the logic of the iterative fitting for …

… An important piece of the puzzle is the limited dissolution of … function for the curve fitting,
both from scipy (v. 1.7.1) library. … first-order transit of solid and dissolved drug forms with a rate …